| CASCADES SA (La Rochette) | Paper and cardboard | 149 | Site |
| PRODIPACT (Montmélian) | Electrical equipment | 144 | Site |
| DELACHAUX (groupe) | Injection system manufacturing | 125 | Site |
| GRAFTECH (Aigueblanche) | Manufacturing of electric materials | 123 | Site |
| AIXAM-MEGA | Automotive industry | 118 | Site |
| ABB Process industrie (site d'Aix-les-Bains) | Conception, production, and installation of machines for the paper industry | 104 | Site |
| TIMET SAVOIE (Ugine) | Development and processing of titanium metal product | 89 | Site |
| OCV RENFORCEMENT (anciennement St Gobain - Chambéry) | Reinforcements and composites | 84 | Site |
| DANFOSS - SOCLA (groupe) | Manufacturing of industrial valves and fittings | 84 | Site |
| GATE France (ST Rémy de Maurienne) | Motor and turbine | 81 | Site |